NIH has a wonderful glossary that will help you to decipher all of the acronyms and abbreviations included in your application instructions or being tossed around at the latest grad student cocktail hour. Every new hire, intern, student, or new investigator I have worked with has been given a copy of this glossary at our first meeting. I highly recommend bookmarking the page and referring to it often with any questions.
Find something that isn't in the glossary? Email me or leave a note in the comments and I will work on getting you an answer.
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