One great resource that I recommend reading is "How to Write a Research Project Grant Application", written by the National Institute of Neurological Disorders and Stroke. While some of the content in NINDS-specific, the page contains quite a bit of informaiton that can be generalized to all research proposals. For example, it provides suggestions on developing your hypothesis, including emphasizing that your hypothesis should be stated in both your abstract and your specific aims.
A word of caution- the site has not yet been updated to reflect the revised research plan guidelines. It still contains sections A through E, which are holdovers from previous requirements. However, some of the advice on getting started is still relevant and very useful.
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