Friday, June 8, 2018

NIH Forms E clinical trials requirements - how's it going?

Have you had your first experience with submission of the new NIH human subjects attachments? Have you written the sections for a clinical trial application?  How did it go?
Since February, I have had the nightmare-inducing task of working on several applications that count as clinical trials under the new guidelines but would not have under the previous ones.  The amount of extra work involved in completion of the text fields and attachments is staggering. Considering that roughly 90% of submitted proposals will not be funded, that is a lot of extra time and financial burden to researchers and administrators.  I hope there are enough complaints from faculty and reviewers to catalyze changes that will minimize this burden.  Perhaps much of this information could be requested at the Just-in-Time stage instead of at the time of proposal submission.  It would save wasted effort and require only those investigators who truly have a chance at being funded to submit their clinical trial details.

Friday, June 1, 2018

R01 deadline is almost here!

Are you still working on your R01 proposal for the June 5th deadline?  Hopefully you have followed all of my tips and have already submitted, verified that your proposal was received by with no errors, and are now enjoying a nice glass of vino. 

If not, best of luck to you as you spend your weekend frantically writing and rewriting Aim 2, checking for typos, and realizing you are still 2 pages over the 12-page limit.  Remember how stressful and awful this is and start earlier for your October 5th submission!

Sunday, May 13, 2018

NINDS will limit awards to well-funded labs

In an effort to focus more resources on junior scientists, the National Institute of Neurological Disorders and Stroke (NINDS) will now limit awards to laboratories that already have funding at levels of $1 million or more.  Although this policy has great intentions, it remains to be seen whether it will lead to increased levels of funding among new and early state investigators.  This article in Science provides more information about the new policy.

Friday, April 27, 2018

How to select which funding mechanism is right for me?

There are many different types of NIH funding mechanisms, and it is easy to get lost in the alphabet soup.  R01, F32, U01, R21 - how do you decide?  To help with this often-encountered confusion, NIH has provided a tip sheet that describes the various funding mechanisms and offers guidance on determining which is appropriate for your project. The document is located here.  This document also provides clarification on the different types of NIH funding instruments, including grants, cooperative agreements, and contracts.  If you are seeking more information, a helpful page on the NICHD website (located here) also provides a nice breakdown.

Friday, March 16, 2018

What does it mean when your NIH grant application is "Not Discussed"?

Although it is a few years old, this helpful article from NIAID provides an overview of the proposal review process that explains what it means for a proposal to be classified as Not Discussed.  This designation is also referred to by some of the old-school folks as "unscored" or "bottom-halved".  Interestingly, the article advises that, in some circumstances, it is a good idea to resubmit a Not Discussed proposal.  This is contrary to a common notion that proposals that are not scored should be significantly revamped and submitted as new.  As the article advises, it is important to contact the appropriate staff member from the relevant Institute/Center to discuss the application and your next steps.

Monday, March 12, 2018

Avoiding Grant Scams

Avoid Grant Scams: No legitimate federal government employee would ever call you and tell you that you qualify or have been approved for a grant for which you never applied. This helpful page from NIH helps you to spot and avoid a grant scam.

Thursday, March 1, 2018

Preliminary data: the perpetual problem of the chicken or the egg

NIAID recently published a helpful article about the importance of preliminary data in strengthening your grant application.  Although this article is somewhat specific to NIAID applicants, the overall message is relevant to everyone: preliminary data is important, and may be your key to getting funded.  Even R21 applications, which by definition do not technically require preliminary data, are strengthened by the addition of relevant preliminary data. 

Wednesday, February 28, 2018

Rare Disease Day- February 28th

Today marks the 11th anniversary of Rare Disease Day.  This day is observed internationally in an effort to bring more attention to rare, understudied diseases.  Here are some events happening today that may be of interest to the academic community:

Want to know more about which diseases are classified as rare?  A full list is located here.

What does the fiscal year 2019 budget mean for NIH funding?

The budget for the 2019 fiscal year proposed by President Trump on February 12th included some modifications to NIH funding.  Importantly, though, the budget would remain at a similar level to the ones in recent years.  This would mean no major cuts or caps on indirects.  However, the new budget does propose the creation of  the National Institute for Research on Safety and Quality, which would replace the Agency for Healthcare Research and Quality (AHRQ), and moving both the National Institute of Disability, Independent Living, and Rehabilitation Research and the National Institute of Occupational Safety and Health (NIOSH) under the NIH umbrella.  The proposed budget also seeks to reduce the amount of salary an investigator can receive from NIH grants and cap the amount of salary each can receive at 90%.  For more information about how the proposed budget impacts the NIH, CDC, and FDA, click here.